CT bone windows

Diagnosis: Fibrous dysplasia

Fibrous dysplasia is a skeletal disorder of unknown etiology in which the medullary cavity is replaced by fibro-osseous tissue. Monostotic fibrous dysplasia makes up 75% of cases most commonly involving the proximal femur, ribs, or the craniofacial bones. Polyostotic fibrous dysplasia is seen in approximately 1/4 of cases. About 1/2 of patients with polyostotic fibrous dysplasia have craniofacial involvement. Albright's syndrome consists of polyostotic fibrous dysplasia, coast of Maine cafe au lait spots, and precocious sexual development. Most patients with fibrous dysplasia present below the age of 30. Craniofacial fibrous dysplasia may be symptomatic from encroachment upon the orbits, neurovascular channels, and paranasal sinuses. On plain film, fibrous dysplasia produces the characteristic ground glass appearance. Other entities which may mimic fibrous dysplasia include neurofibromatosis and Paget's disease. Related Cases

Craniometaphyseal dysplasia Renal cell mets Fibrous dysplasia